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Climadan (Clindamycin)
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Clindamycin

Climadan is an antibiotic used to treat the respiratory tract, abdomen, skin, pelvis, vagina, bones and joints, and is available by injection, capsule, foam, gel, or oral solution. It can also be used to treat malaria and some methicillin-resistant Staphylococcus aureus (MRSA) infections. Climadan phosphate is also available in a combination drug in topical cream form (Duac) used to treat acne. Climadan is manufactured by Pfizer. Despite the efficacy of Climadan treatment of a multitude of infectious conditions, serious potential adverse effects in the use of the medication have been identified. Among the more severe of its more common adverse effects is Clostridium difficile-associated diarrhea that can lead to pseudomembranous colitis. Pseudomembranous colitis is a serious condition that can progress to toxic megacolon, which can result in perforation of the colon, invasion of the bloodstream by virulent bacteria, and even death.

Other names for this medication:
Clindamycin, Cleocin, Acnestop, Aknet, Albiotin, Antirobe, Basocin, Bexon, Biodasin, Clendix, Clidan, Clidets, Climadan, Clinacin, Clinda, Clindacin, Clindacne, Clindagel, Clindahexal, Clindal, Clindamax, Clindamicina, Clindamycine, Clindasol, Clindasome, Clindesse, Clindets, Clindoral, Clinex, Clinfol, Clinidac, Clinika, Clinimycin, Clinium, Clinsol, Cliofar, Cliz, Cluvax, Cutaclin, Dacin, Daclin, Dalacin, Dalacine, Damicine, Dentomycin, Dermabel, Divanon, Evoclin, Fouch, Klamoxyl, Klimicin, Klindacin, Klindamicin, Klindamycin, Klindan, Lanacine, Lindan, Medacin, Mediklin, Milorin, Myclin, Prolic, Rosil, Sobelin, Tidact, Topicil, Torgyn, Trexen, Turimycin, Ygielle, Zindaclin,

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Vaginal Climadan comes as a suppository to place in the vagina and a cream to apply to the inside of the vagina. The vaginal suppositories are usually used once a day, preferably at bedtime, for 3 days in a row. Most brands of the vaginal cream are used once a day, preferably at bedtime, for 3 days in a row or for 7 days in a row. One brand of vaginal cream (Clindesse) is usually used as a single dose, given at any time of day. If you are using more than one dose of vaginal Climadan, use it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use vaginal Climadan exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

This medication is for vaginal use only. Do not swallow the cream or suppositories, and do not apply the cream to any other part of your body. Be careful not to get the cream in your eyes. If you do get the cream in your eyes, rinse your eyes with plenty of cool water.

Your medication will come with directions for use. Read these directions and follow them carefully. Ask your doctor or pharmacist if you have any questions about how to use vaginal Climadan.

Use vaginal Climadan until you finish the prescription, even if you feel better. If you stop using vaginal Climadan too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

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The forelimbs are normally loaded and the movement of its hindlimbs is free without weight bearing. Our results suggest that in non-diabetic, there is an inverse relationship between bone mineral density in lumbar spine and BMAT and a trend persists after adjustment for weight, age, BMI and height. The patients completed a questionnaire and were examined to determine the presence of fatigue and whether they fulfilled the ACR criteria for FMS. No statistical differences were found in the amount of mechanoreceptors among distal, middle, and proximal parts of the ligaments. A history of the International Neuropsychological Society: the early years (1965-1985).

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Calibration was performed in vitro by using glass capillaries containing blood at several Hb concentrations, equilibrated at various oxygen tensions. Nitric oxide in the medial prefrontal cortex contributes to the acquisition of cocaine place preference and synaptic plasticity in the laterodorsal tegmental nucleus. Inner ear hair cell regeneration in a mammal: identification of a triggering factor. In vitro experimental tests were carried out on the PDL specimens of adult pigs to obtain stress-relaxation and cyclic stress-strain curves.

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It allows tumor staging and, therefore, treatment planning to be more intelligently performed. Pulmonary specimens obtained from ten normal subjects and 53 patients with various pulmonary diseases were studied with energy-dispersive x-ray analysis. By increasing the expression of nicotianamine synthase (NAS), we fortified the level of bioavailable iron in rice seeds. Duct size as determined by LICU corresponded precisely with cholangiography.

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In vitro Ig synthesis and antilymphocyte antibody in monozygotic twins discordant for systemic lupus erythematosus. Tomotherapy plans led to a significantly higher low dose exposure to the lungs and contralateral breast. We also discuss the possible implications of these findings for the design of a therapeutic regimen relying on combined targeting of key effectors of both pathways. As a result, there was no significant difference in mucosal blood flow between the antrum and the corpus during histamine stimulation.

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A chest X-ray revealed cardiomegaly and bilateral pulmonary edema suggestive of congestive heart failure. The Electronic Residency Application Service was used to obtain applicant data and program match outcomes at 33 independent surgery programs. The colposcopic findings in 86 virgin teenagers are reported and compared with a matched control group of 172 sexually active teenagers. Furthermore, ethnobotanical analysis will provide data on sustainable use and valorization of this plant heritage for ethnopharmacological and phytochemical studies.

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The first half of the century was blighted by world wars, economic depression and post-war austerity. The use of restrictive covenants, involvement in self-referral patterns, and maintaining appropriate comity among physicians while engaged in the marketplace are common challenges in radiation oncology practice. Twenty patients with knee OA and 20 healthy controls completed 30 minutes of treadmill walking. Randomized clinical comparison of endodontically treated teeth restored with amalgam or with fiber posts and resin composite: five-year results. determined using the trapezoidal method, were obtained for a Markov simulation that would allow for determining the likelihood of achieving a AUC0-24 h/MIC ratio above 70 for infections caused by susceptible B.

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Here, we examine the differences in the dynamics of a minimally restructuring protein, EcoRI, when it is bound to its cognate DNA and to a noncognate sequence which differs by just a single basepair. A very tight contact is present between the apical membrane of the tormogen cell and the cuticle of the hair base in olfactory sensilla trichodea of Antheraea polyphemus. Microsomes accumulated process appears to be gradual requiring many minutes which may explain the gradual increase in intensity of the inhibitory effect with increased time of exposure to DES. Thermoreversible gel for delivery of activin receptor-like kinase 5 inhibitor SB-505124 for glaucoma filtration surgery. SMAD4 gene mutation increases the risk of aortic dilation in patients with hereditary haemorrhagic telangiectasia.

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Antibody and DNA probe hybridization studies showed that expression initially occurs in the ovary wall and then switches to the aleurone and ventral furrow of developing seeds, reaching a peak in the doughy stage. Increased expression of VEGF in degenerative disc disease increases the levels of inflammatory cytokines and nerve ingrowth into the damaged discs. As an alternative, large animal models should be explored as a potentially better approach for clinical translation of cellular therapies.

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Similarly, bronchoalveolar lavage fluids from the animals showed chemotactic activity for peripheral blood neutrophils. This paper describes the prevalence of various sexual behaviors in a nationally representative sample of adults in the United States.

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In this study the single as well as combined effects of quartz, ozone and nitrogen dioxide (NO2) on some immunofunctions of bovine alveolar macrophages (BAM) were investigated. The data can be explained by the concept of a widely distributed system of functionally differentiated but coordinated atrial pacemakers. Computer simulations demonstrate how the algorithm effectively eliminates the depth of field limitation.

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HFMD usually causes only mild illness with no long-term consequences. Both isoforms in isolation exhibit tumor suppressor properties and we show here similar cellular locations on mitochondria and microtubules, paclitaxel-like microtubule hyperstabilization, disruption of mitosis, and interaction with C19ORF5. A large scale analysis of cDNA in Arabidopsis thaliana: generation of 12,028 non-redundant expressed sequence tags from normalized and size-selected cDNA libraries. In the present study, we determined the expression and subcellular distribution of HOXA10 and its downstream molecule, p57, in ESC during in vitro decidualization induced by a combination of 8-bromo-cAMP and medroxyprogesterone acetate. fumigatus) hyphae antigens induced the release of interleukin-8 (IL-8) in anti-fungal innate immunity of cultured human corneal epithelial cells (HCECs) and determine the involvement of intracellular signalling pathways.

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Cytomorphological changes of the bone marrow and changes of the blood proteins in reticuloses Comparison of the Parisian V3 loop sequences with other published data indicates that the range of diversity in France is included within that of a large group that contains sequences from North America, the rest of Europe, Japan, India and Africa.

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In this study, the analgesic efficacy and safety of rofecoxib in thoracotomy patients were evaluated. We have also discussed the pathogenesis and treatment options for the ranula.

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This paper resumes first experiences with a special offer for relatives. In all cases, activation involves their recruitment to the sites of damage.

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At the molecular and cellular levels, ROCK upregulates several molecules related to inflammation, thrombosis, and fibrosis. Consistent with these alterations, larval neuromuscular junctions of Cog7 mutants exhibit a significant reduction in bouton numbers.

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Dose-limiting toxicities (DLTs) were monitored during the first cycle. Hepatocytes in the subcultured cells were examined by the expression of hepatocyte markers. Synthesis and anticholinergic activity of some new N,N-disubstituted carbamodithioic acid 2-oxo-2-(diphenylamino) ethyl esters. Mesenteric lymphadenopathy has been rarely reported in pediatric patients with Gaucher disease, developing despite the enzyme replacement therapy.

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Osteoclast surface is markedly decreased in bFGF-treated rats, but this finding may be secondary to the extensive osteoid surface in these animals. Importance of routine mediastinal staging in women with non-small cell lung cancer Longitudinal Observations on the Mineral Metabolism of Dialysis Patients at the University Hospital. Unsuspected orbitocranial penetrating injury by a plastic pen cartridge: case report. Special instructions and interventions need to be designed to help these smokers develop a broader definition of health as more than the absence of disease, a greater sense of internal control over health practices, and an increased sense of power for participating in behavioral change.

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Intramuscular haemangioma of the chest wall is very rare, and only few cases associated with rib destruction has been reported. Arginine 66 residue of Fur is required for the regulatory function of this protein in the acid adaptation mechanism of Helicobacter pylori. The effect of ABCG1 deficiency on atherosclerotic lesion development in LDL receptor knockout mice depends on the stage of atherogenesis. Commentary: Torpor: The Rise and Fall of 3-Monoiodothyronamine from Brain to Gut-From Gut to Brain? Recommendations are made for the planning and development of future disaster support services.

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Diagnosis and therapy of coagulopathies in patients with liver disease. Four unusual cases of autodestruction of the penis are described with their aetiology, diagnosis and management. Turbidimetry of inorganic sulfate, after precipitation with barium sulfate, can be done simply in a Cobas Bio centrifugal analyzer.

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Chylous effusions secondary to pancreatitis: case report and review of the literature. The morphology of the larval stages is compared with previous work on H. Chromatographic separation is achieved by two gradient elutions (two injections per sample), starting at different pHs, on a reverse phase Agilent Zorbax Eclipse C(18) column AAA (4.6 x 150 mm). The indications and role of blocks in pain management are discussed. These enzymes are believed to act via ATP-dependent binding of AMP to their substrate.

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With baseline measures and body mass index controlled for, analysis of covariance showed that the video game provoked significant and incremental cardiovascular reactivity across the games in adolescents when compared with the two other groups of children. Altogether, these data suggest that the cell division machinery assembly is driven by the cooperative association among the different Fts proteins to form a dynamic multiprotein structure at the septum site. Method of Breast Reconstruction Determines Venous Thromboembolism Risk Better Than Current Prediction Models. Anorexia nervosa (AN) is a disabling, deadly and costly mental disorder.

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Clinicians are often challenged when making return-to-play decisions following anterior cruciate ligament reconstruction (ACL-R). Suitable Days for Plant Growth Disappear under Projected Climate Change: Potential Human and Biotic Vulnerability. Sitting With Fatima: How Longitudinal Learning Inspired My Passion for Obstetrics and Gynecology. The effect of tuberculin-desensitization alone or combined with chemotherapeutic agents on experimental tuberculosis In contrast, OaN6 transcripts were detected in all tissues except for liver and heart.

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Spontaneous pancreaticoduodenal fistulization and arterial psuedoaneurysm formation are both complications of acute pancreatitis. Mesomorphism and electrochemistry of thienoviologen liquid crystals. Mediastinal emphysema as a complication of pneumoperitoneum therapy.

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Despite the persistence of viral early mRNA for at least several hours, synthesis of virus-induced polypeptides occurred only during the first hour and was followed by abrupt inhibition of all protein synthesis. Besides, a study was made of the ultrastructure of the arterioles and sinusoidal capillaries of the liver.

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Light microscopy revealed findings of membranoproliferative glomerulonephritis. The method was applied to the late-stage derivatization of pharmaceuticals having a chloro group. To study genotype-phenotype correlations, we evaluated the clinical and laboratory data of 51 genetically proven A-T patients, and additionally measured ATM protein expression and kinase activity. In vitro NK-activity and in vivo resistance to leukemia: studies of beige, beige//nude and wild-type hosts on C57BL background. The decision to perform relaparotomy is often difficult, and this study aimed to develop a clinical model to aid the decision-making process.

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Persistent organochlorine residues and their accumulation kinetics in Baikal seal (Phoca sibirica) from Lake Baikal, Russia. Different non-invasive and invasive procedures are available for screening. The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation. Renegotiating expertise: an examination of PACS and the challenges to radiology using a medical anthropologic approach.

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Creation of a multi-segmented optical needle with prescribed length and spacing using the radiation pattern from a sectional-uniform line source. Output Factors and dose profiles measurements performed, respectively, with the PSD and the PSDCA were in agreement with those obtained with the UD and EBT2 films. Inclusion of push-pull N-methylpyridinium salts within surfactant hydrogels: is their excited state intramolecular charge transfer mediated by twisting? We discuss the long-term results of 8 spinal HC patients who were monitored at our clinic for 7-15 years. As indicated in this paper, studies have demonstrated that the UPSIT can identify most malingerers and is sensitive to age, gender, smoking habits, and a wide variety of olfactory disorders.

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We demonstrate that UBXD8 is an essential determinant of metabolically stimulated degradation of HMGCR and of cholesterol biosynthesis in multiple cell types. Several of these factors are modifiable, and provide important targets for researchers, clinicians, and public health practitioners in their efforts to reduce the burden of disability in the older population. In vitro evolution was used to develop a DNA enzyme that catalyzes the site-specific depurination of DNA with a catalytic rate enhancement of about 10(6)-fold. Site-directed mutagenesis is now used to determine that the minimal sequence requirement for conferring the full range of beta-tubulin autoregulation is the amino-terminal tetrapeptide MR(E/D)I. The risk associated with poisonings in children was assessed on 6175 subjects admitted to the pediatric hospitals of 3 regions of Northern Italy between 1975 and 1990.

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glaseri (Nematoda: Steinernematidae) was observed in strawberry fields in Vancouver, WA. Patients with type 3 Gaucher disease have been subclassified into types 3a and 3b. The structure recognized by the A10 monoclonal antibody, although strikingly structurally similar to the HLA-A,B,C complex, is immunologically different both from histocompatibility antigens and from beta 2 microglobulin. In addition, patients in the coaching group participated in four telephone sessions with an advanced practice nurse interventionist using motivational interviewing techniques to decrease attitudinal barriers to cancer pain management. Finally, we describe parallel emergence of theta oscillations, theta-mediated neuronal activity and behaviors during development.

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Pneumococcal HSP40 induces the immune response in mouse macrophages via p38MAPK and JNK signaling pathways Perspective: genetic and hormonal roles in bone disorders: insights of an updated bone physiology. No blood transfusion and dialysis were needed during perioperative period. They can help us discern which moral concepts are operative in a specific instance. Vitamin E exhibits concentration- and vitamer-dependent impairment of microsomal enzyme activities.

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Toxicity of threadleaf groundsel (Senecio douglasii var longilobus) to cattle. Whole-genome cartography of p53 response elements ranked on transactivation potential. Alteration of evolution of delayed neuronal death in the gerbil after intraperitoneal injection of nicardipine was investigated by using immunohistochemistry for microtubule associated protein (MAP) which enables early detection of ischemic injuries. Outcome evaluation euglucon dosage of aspirin of behavioral parent training and client-centered parent counseling for children with conduct problems. Thorny ganglion cells in marmoset retina: Morphological and neurochemical characterization with antibodies against calretinin.

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