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Simvastatina (Simvastatin)
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Simvastatin

To investigate the effect of Simvastatina on the function of MG63 cell line. These results suggest that the diverging impact of Simvastatina and atorvastatin on plasma HDL-C levels in humans may be attributable, at least partly, to a greater production rate of apoA-I with Simvastatina.

Other names for this medication:
Simvastatin, Zocor, Actalipid, Lipex, Lipinorm, Lodales, Simcard, Simgal, Simvastatina, Simvor, Sinvacor, Sivastin, Vasilip, Zeid, Zocord, Zosta, Zostin,

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Simvastatina belongs to a group of medicines called statins.

It's used to lower cholesterol if you've been diagnosed with high blood cholesterol. It's also taken to prevent heart disease, including heart attacks and strokes.

Your doctor may prescribe Simvastatina if you have a family history of heart disease, or a long-term health condition such as rheumatoid arthritis, or type 1 or type 2 diabetes.

The medicine is available on prescription as tablets. You can also buy a low-strength 10mg tablet from a pharmacy.

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Our objective was to better define the activity/feasibility of gemcitabine/cisplatin (GC) as induction chemotherapy in patients with stage IIIA N2 non-small-cell lung cancer (NSCLC) followed by surgery or radiotherapy within a large, ongoing comparative study (EORTC 08941). This retrospective cohort study from 1997 to 2003 compares 140 myeloablative and 129 nonmyeloablative patients from the Fred Hutchinson Cancer Research Center. Yin Yang 1 extends the Myc-related transcription factors network in embryonic stem cells. Renal cell carcinoma with thrombus in the inferior vena cava: extracorporeal circulation and deep hypothermia without open-chest surgery.

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Cultural developmental research has focussed primarily on the emergence and development of prosocial behaviour, and would benefit from an examination of the interplay between psychological (cognitive, motivational) and sociocultural (norms, developmental niche) foundations over ontogeny. Click-evoked otoacoustic emissions and acoustic brain stem potentials in early detection of hearing disorders in premature and newborn infants after neonatal critical care We report two cases of iliac bone surgery (repair of a symphysis disjunction and fixation of a fracture of the iliac ala) where TAP blocks were effective for postoperative analgesia. The unsymmetrical core-expanded BODIPY with annulated indole and benzofuran rings was also synthesized by stepwise and regioselective nucleophilic substitution and palladium-catalyzed intramolecular C-C coupling reaction.

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We show that BAT phenotype is altered from day 5 of gestation, implicating early pregnancy factors, which was confirmed by reduced expression of BAT markers in progesterone challenged oophorectomised mice. Freezing in the primary polyvinylchloride plastic collection bag: a new system for preparing and freezing nonrejuvenated and rejuvenated red blood cells. The estimated effect of the policy change in 1978 was modest compared with results presented in most earlier studies regarding the privatization of wine sales in other jurisdictions. As knowledge and techniques develop in predicting genetic conditions, more genetic services are being established. Rapid and complete switching between the N6 and the N5O donor set induced by changing the metal oxidation state has been observed for a new structural motif based on a ruthenium(II) polypyridyl complex.

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Attachment occurred simultaneously in the intercaruncular and caruncular regions near the embryo and subsequently spread towards each end of the blastocyst. Five electronic databases were searched: (1) Medline Current, (2) Medline In-process, (3) PsycINFO, (4) Econlit and (5) Web of Science. Post-traumatic growth disorders and corrective measures on the growing skeleton

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With constant applied normal and shear stresses, the thickness of the solvent layer is a non-monotonic function of time with a maximum because the solvent flow from the gel to the solvent layer is dominant in the short time scale and the solvent flow from the solvent layer to the outside is dominant in a longer time scale. 16S acetylcholinesterase of the extracellular matrix is assembled within mouse muscle cells in culture. The threshold and latency of the human flexor reflex were recorded by different kinds of electrical stimuli in order to find the optimal stimulus, defined as the lowest amount of currency and the shortest possible duration. The purpose of this retrospective study was to compare the functional outcomes of patients who had mandibular resection and reconstruction with and without prosthetic intervention, and to identify predictive factors that may have an impact on functional outcomes. A comprehensive MEDLINE search was performed of pertinent studies in the literature relating to the use of LHRHa and skeletal muscle.

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The Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol. Driving endonuclease genes (DEGs) spread through a population by a non-Mendelian mechanism. Paper mill workers have frequent and prolonged exposure to skin irritants and allergens and may have a higher risk of developing occupational dermatitis.

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Evidence for a decisive role of nicotine in cigarette smoking evoked distortions of gastrointestinal tract functioning is provided. From the studies reviewed it is apparent that gamma globulin is of value in preventing hepatitis both when administered as mass prophylaxis in an epidemic, and when given to persons in close contact with a person who has the disease. Dual treatment with atazanavir-ritonavir plus lamivudine versus triple treatment with atazanavir-ritonavir plus two nucleos(t)ides in virologically stable patients with HIV-1 (SALT): 48 week results from a randomised, open-label, non-inferiority trial. The extra proton in the active site decreases the proton coupled reduction potential for CuB by almost half a volt, leading to agreement with titration experiments.

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Moreover, production of reactive oxygen species (ROS) indicated by the superoxide dismutase expression and the unfolded protein response of the mitochondria was found systemically involved in the initiation of these processes for both two site irradiation. Delayed Avascular Necrosis and Fragmentation of the Lunate Following Perilunate Dislocation. We have used this technique to select recombinants carrying inserts concentrated on chromosome 21. Long-term prognosis and a prediction model for acute bowel ischaemia following cardiac surgery.

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The risk of neonatal death and morbidity in second-born twins is higher in the group in which both twins were delivered vaginally and the group in which the second twin was delivered by cesarean delivery after the first twin was delivered vaginally compared with the group in which both twins were delivered by cesarean delivery. Means of improving the hydrodynamic characteristics of an aortic valve xenobioprosthesis The method offers possibility of variation in the drug delivery that is not possible with the ganciclovir implants. South-East region of Poland includes six voivodeships, with about 3.6 mln of inhabitants.

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The case presented illustrates the potential of assessing fetal pulmonary maturity by analysing liquor draining vaginally after premature rupture of the membranes. On the introduction of genetically modified Leishmania outside the laboratory. Data from the PCR arrays showed that repeated stress significantly increases the transcript levels of several genes associated with cellular proliferation, including proto-oncogenes. Current modes of treating Stage III rhabdomyosarcomas are reviewed. Systems and methods for inspection of the functioning of sewage disposal plants.

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Apart from cancer therapy, it is also utilized in the imaging and multimodal therapy of cancer. Interestingly, the Pim-promoted metastatic growth of the orthotopic xenografts is associated with enhanced angiogenesis and lymphangiogenesis. This study aims to explore the correlation between microRNA-143 (miR-143) expression in peripheral blood mononuclear cells (PBMCs) and disease severity in patients with psoriasis vulgaris. Direct in vivo protein transduction into a specific restricted brain area in rats. In addition, it aims to highlight key areas for future research.

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Bionomics of the vectors of onchocerciasis in the Ethiopian geographical region. In conclusion, hypothyroidism resulted in a delayed growth of the tumor, but it did not affect the malignant features of the neoplastic cells. Paracellular permeability was followed by monitoring transepithelial electrical resistance variations and by observing zonula occludens-1 distribution.

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Morphine was substituted with placebo for 60-hour periods to compare the effects of abstinence with those of continued use. Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex.

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The method was applied for sporocysts and cercariae obtained from the golden mussel Limnoperna fortunei collected in the Uji River, Japan. Reading the Mind in the Eyes Test (RMET) was used as a measure of emotion recognition, and neuropsychological tests and questionnaires were utilized as executive function measures. Choledochoduodenostomy in the prevention and treatment of patients with common bile duct stones has been frequently discussed during several years. At acidity levels below pH 7, low concentrations of nitrite (0.2 mM) caused effective complete killing of S. From the perspective of avoidance of adverse events, erythropoietin does not appear to be an efficient use of limited resources for routine use in critically ill patients.

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Levels of immunoreactive ANP (irANP) increased from a mean (SD) of 23 (15) pmol/l to a maximum of 94 (41) pmol/l. Neurotensin increases net fluid secretion and transit rate in the small intestine of man. Akt is activated by phosphorylation of two key residues: Thr308 and Ser473.

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Sri Lanka is an island nation in Indian Ocean that provides free healthcare to all citizens through government healthcare system. Transient expression of a Ran/TC4 mutant protein deficient in GTP hydrolysis blocked DNA replication, suggesting a role for Ran/TC4 in the regulation of cell cycle progression. In conclusion, height, weight and BMI relationship with hemodynamic and arterial stiffness parameters differs in patients with and without CKD. The term polyphenol comprises thousands of molecules presenting a phenol ring and are widely distributed in plant foods. Synaptophysin is a presynaptic vesicle protein and a marker of synaptic density.

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Some comparisons between modeled and measured glottographic waveforms are made. After a revision of arbitrary drug names and the deletion of duplicated submissions, AERs involving 5-FU and oral fluoropyrimidines were analyzed. We herein report a case of renal colic caused by a shotgun pellet lodged in the ureter seven years after the injury. OS and EFS were determined using the Kaplan-Meier method and compared using the log-rank test.

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The relationship of IEI and psychiatric disorder is important to acknowledge because it alerts clinicians to the fact that many persons diagnosed with IEI suffer treatable emotional illnesses, and because it suggests that some persons with mental illness are being misdiagnosed when their symptoms are misinterpreted as evidence of IEI. To better understand and further improve nanomedicine-mediated drug targeting, it is important to design systems and strategies which are able to provide real-time feedback on the localization, the release and the therapeutic efficacy of these formulations.

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The erythematous macules are covered with numerous vesicles and pustules with occasional hypopyon formation. Cases of synchronous triple cancers of the esophagus and other organs curatively resected are rare. The effects of oral midazolam or intramuscular atropine and pethidine used as premedication in two groups of 35 children over 5 years of age were studied. The results revealed a pattern of similarity between the time points for those who were on exclusive breastfeeding or predominant breastfeeding.

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Appraising the effect of globalisation on professionalism involves assessing its effects at the intrapersonal, interpersonal, and institutional levels, and its effect on society at large. Gastrojejunostomy stricture following LRYGBP is associated with substantial morbidity and patient dissatisfaction. Isolating gait-related movement artifacts in electroencephalography during human walking. Additionally, in contrast to current models of gene sequence evolution, models of transcriptome evolution often lack the sophistication to effectively determine whether transcriptional differences between species or within a clade are the result of neutral or adaptive processes. The physis remains relatively transverse throughout development although contouring occurs under each tibial weight-bearing compartment.

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The deprotonation of Glu-90 during the photocycle is elucidated by time-resolved FTIR spectroscopy, which seems to be part of the opening mechanism of the conductive pore. In the cadmium-induced hemolysis, the reaction products of the antirheumatic drugs with the membrane protein presumably cannot cause an increase in surface area/volume ratio of the erythrocytes, which is generally regarded as a cause for stabilization. This means that respiratory therapists (RTs) should be effective consumers, users and producers of scientific research pertaining to respiratory therapy technology and respiratory physiology. Synovial fluid omentin-1 levels showed an independent and negative correlation with radiographic severity of the disease in patients with knee OA. Alternative names to this syndrome are Type I hyper lipoproteinemia and familial lipoprotein lipase deficiency.

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After cleaning the dataset, the final count of SNOMED CT concepts in the nursing problem list subset is 369. Pure erythrocytosis classified according to erythropoietin titers. Implicit verbal coding of visual information for normal and learning disabled readers. Furthermore, subgroup analysis according to ethnicity indicated that ICAM-1 rs5498 polymorphism decreased the risk of MI among Caucasian and Asian populations. A mouse model of HAND is discussed, which demonstrates mild behavioral deficits and has been used to investigate cART and novel treatments for HAND.

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Both of these cholesterol-independent effects result from an apoE3-mediated induction of cyclooxygenase-2 (Cox2). Changes were analyzed according to three cross-sectional moments of evaluation: one moment previous to intervention, another one when it was finished and finally, one at five years of finishing it.

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In the not-too-far future, it could displace and evict riparian vegetation and the biota it supports. The lesion-induced behavioral asymmetry and its partial compensation may be one of the determinants of the observed neuronal plasticity. During subsequent blood bank storage, these WBC-reduced PCs display, in comparison with standard PCs, normal in vitro platelet properties, decreased accumulation of cytokines IL-6 and IL-8, and increased complement activation. We report cognitive profile and seizure characteristics in seven patients with GGE and GPFA.

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Selected examples of the effects of parasitic infection on food intake, intestinal propulsion and motility, organ function, epithelial structure and function, and intestinal circulation are presented. More and more efforts are put in either converting a fluorescence label into an electron dense product or preserving the fluorescence throughout preparation for the electron microscopy. Comparative effectiveness research: using systematic reviews and meta-analyses to synthesize empirical evidence. What can patterns of differentiation across plant genomes tell us about adaptation and speciation?

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This hypothesis was investigated by analyzing complex formation of recombinant murine VASP with actin after phosphorylation with cAMP-dependent kinase in different assays. Some possible physiological actions of these ascorbic acid metabolites are discussed.

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The component latencies of all the BI responses derived from the contralateral channel were significantly prolonged compared with those derived from ipsilateral and non-cephalic channels. In tissue sections, disruption of the interglandular epithelium and presence of amebic ulcers and of large numbers of trophozoites were most noticeable 10 days p.i. Climbing fiber (CF) afferents modulate the frequency and patterns of cerebellar Purkinje cell (PC) simple spike (SS) activity, but its mechanism is unclear. Different contribution of interleukin-6 and cortisol activity to total plasma fibrin concentration and to acute mental stress-induced fibrin formation. This suggests that obstructive stenosis at the level of the pancreatobiliary junction (but not the ampulla) may be a causal factor in a proportion of choledochal malformations.

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Thrombo-embolism as a complication of prosthetic replacement operations of the hip: prophylaxis with heparin at low doses. Intercellular Signaling in Cancer-the SMT and TOFT Hypotheses, Exosomes, Telocytes and Metastases: Is the Messenger in the Message?

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There was not enough evidence to suggest that the included drugs reduced bedwetting. However, such models require large training datasets in the case of multi-object structures, since it is required to obtain not only the individual shape variations but also the relative position and orientation among objects. These data suggest that ASA acts by inhibiting 1 alpha OH-D3 induced bone resorption. We studied the cases of twenty-one patients with the syndrome of thrombocytopenia and absent radius. Here, too, a trend towards positive results was observed, although in one case, disordered wound healing was seen.

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Four latex-injected cadaveric heads (eight sides) underwent dissection in which frameless stereotactic guidance was used. We have used in situ hybridization to study the expression of mRNAs for L1 and its close homologue CHL1, by neurons regenerating their axons in vivo, and have compared CAM expression with that of GAP-43.

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We propose a novel approach for evaluating parcellation based on measuring the degree to which parcellation conforms to known principles of brain organization, specifically cortical field homogeneity and interhemispheric homology. The kinetics of aggregation, crystallization and defect formation are followed in real time.

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The Pr55(Gag) molecule directs the assembly process and is sufficient for particle assembly in the absence of all other viral gene products. GFP-CSA is also mobile but does not concentrate at discrete foci. GEE analysis showed that smoking was a risk factor for early implant failure, and several risk factors were identified for late implant failure. Weekly paclitaxel is modestly effective and safe in docetaxel-resistant metastatic breast cancer patients.

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To investigate changes in the surgical treatment of gallstones during a 10 year period. Association between A-kinase anchor proteins 12 methylation and recurrence of hepatocellular carcinoma

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The ectopic FOXL1 expression increased the expression of p21 and p27, which induced G1 arrest in the U-2 OS cells. Macrophages express a broad range of plasma membrane receptors that mediate their interactions with natural and altered-self components of the host as well as a range of microorganisms. The reversed gradient reduces the trans-membrane proton-motive force available to energize ATP synthesis. These changes, however, were not accompanied by significant alteration in bone material properties as assessed by a 3-point bending test. Although effects of CHI on hippocampal formation volume might be difficult to demonstrate in non-fatal paediatric CHI, further investigation using functional brain imaging could potentially demonstrate hippocampal dysfunction.

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Unnatural amino acid technology provides a degree of bioorthognality and specificity not feasible with other methods. The influence of socioeconomic deprivation on early outcomes in vascular access surgery.

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simvastatina cinfa 40 mg 2016-05-29

Bone cement and plastic materials were found in the joint capsule, in the bone marrow of the distal part of the femur, but they were not present in the lymph nodes. The majority of osteoclasts require mRNA and protein synthesis for bone resorption in vitro. For selecting likely response to endocrine therapy, both estrogen losap sleep over receptors (ER) and progesterone receptors (PR) should be measured.

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Here, we identified several tyrosine-phosphorylated proteins using mass spectrometric analysis in response to LPS stimulation. The aim of the study was to define the relationship between parameters of immune activation and EBV load in HIV-1-infected subjects. This study demonstrated that contrast-enhanced ultrasound has the ibumax 400 mg equals how many teaspoons potential to be used as a minimally invasive and cost-effective alternative method for outpatient shunt malfunction diagnosis.

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Microscopic anatomy of a femoral head after resurfacing arthroplasty: a case report. Experimental research and clinical experience have shown that the administration of 50 000--100 000 U of an antibiotic (kanamycin, monomycin, hectamycin, chloramphenicol) into the wound soon after an open penetrating eulexin keflex uses injury had been inflicted to the skull and brain protects the wound from microbial contamination. Computed tomography of the abdomen demonstrated obturatory node metastasis. Early recognition and prompt medical therapy will generally successfully treat the condition.

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rs8099917 SNP is probably associated with the response to interferon treatment in HBeAg-positive patients with chronic hepatitis B, and Allele G may be predictive of the treatment cilostazol renal dosing clindamycin success. Diluted gadodiamide (a gadolinium-based contrast agent) was administered to the bilateral tympanic cavity by injection through the tympanic membrane.

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Crim1 has an essential role in glycogen trophoblast cell and sinusoidal-trophoblast giant cell development in the placenta. These results suggest that the enhancement of neutrophil pexeva reviews of fuller migration by low levels of auranofin is related to the enhancement of cGMP levels in neutrophils. MiR-96 targets SOX6 and promotes proliferation, migration and invasion of hepatocellular carcinoma. A systemic coordination of such models provided a complete continuity in the activities of hospitals, dispensaries and intermediate subunits.

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They both encode putative RNA-binding proteins of the RRM (RNA recognition motif) type, and the high degree of conservation of both these gene families suggests an important role in spermatogenesis. Studies of conformational changes have mainly been performed in vitro using sophisticated physical and biochemical methods that usually require purified proteins. The resulting shift of the psychometric curve showed that recognition became biased toward the identity of the prime. The active zeldox dose range drug did increase total sleep time (p less than 0.001) and thus was an effective hypnotic in patients with COPD. Our technique utilizes a percutaneous approach with minimal fracture exposure.

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A general linear model was applied to analyse the effects of smoking, the year of examination, age, and duration of exposure to asbestos. The diagnosis and treatment of this condition require a thorough understanding seropram effects secondaires traitement sida of the lacrimal apparatus and its ocular and nasal relationships. It has become problematic because most of the isolates are resistant to multiple antibiotics, and therefore, development of phage therapy has attracted strong attention. The development of echogenicity required the presence of fibrinogen or its products plus erythrocytes.

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Growth characteristics of polylysogenic culture of Bacillus thuringiensis subspecies galleriae in a chemostat Elevated circulating levels of serum tumor necrosis factor-alpha in eupantol iv patients with hemodynamically significant pressure and volume overload. Sleep oxygen desaturation and circulating leptin in obstructive sleep apnea-hypopnea syndrome. The exhausting dilemmas faced by home-care service providers when enhancing participation among older adults receiving home care.

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Histamine H1 antagonists rarely cause drug-induced lung injury (DLI). As a mean to encourage the solution of this situation, we review the historical progress in the taxonomy of the group, including some comments on generic and specific delineation, and recommend some critical steps to solve the current confusion. In contrast, the center excitation remained unchanged or increased suggesting a parallel decline of the inhibitory surround. Air bipreterax 5 mg vidal Force Aerospace Physiology Training Units prior to and immediately following hypoxia training in the hypobaric chamber. This study sought to describe the characteristics of dog bite injuries to aid in promoting healthy environments for children.