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Moreover, the enhancement of the response to compound 48/80 observed after Catafast treatment was prevented by local administration of PGE2 (30 nM). Incidence of upper gastrointestinal adverse events was low in both treatment groups (0.5 percent versus 2.2 percent for celecoxib and Catafast SR, respectively).

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Catafast is used to relieve pain, swelling (inflammation), and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat other painful conditions (such as dental pain, muscle aches, pain after surgery or after having a baby). However, if you have sudden severe pain and want quick relief, it may be better to use other pain medications that are faster acting than this medication. Consult your doctor or pharmacist for more details.

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