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Dutasteride is used to treat benign prostatic hyperplasia (BPH), which is also called enlarged prostate. When the prostate is enlarged, it can pinch or squeeze your urethra and make it harder for you to urinate. Dutasteride helps increase your urine flow and decrease your risk of a complete blockage of urine flow (acute urinary retention). In some cases, these actions can reduce the need for prostate surgery.

Other names for this medication:
Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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Dutasteride is used alone or with another medication (tamsulosin [Flomax]) to treat benign prostatic hyperplasia (BPH; enlargement of the prostate gland). Dutasteride is used to treat symptoms of BPH and may reduce the chance of developing acute urinary retention (sudden inability to urinate). Dutasteride may also decrease the chance that prostate surgery will be needed. Dutasteride is in a class of medications called 5-alpha reductase inhibitors. It works by blocking the production of a natural substance that enlarges the prostate.

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In order to define a cellular model suitable for studying, in vitro, the molecular properties and functions of neurotrophin receptors in human lymphocytes, TrkA, TrkB, TrkC and p75(NTR) expression was investigated in a panel of EBV immortalized lymphoblastoid (LCL) and Burkitt lymphoma-derived cell lines (BLs) compared to primary B lymphocytes by RT-PCR and flow cytometric analysis. Studies on the development of tuberculin sensitivity in immunized guinea pigs with demonstration of a close relationship between results of skin tests and the lymphocyte transformation technique.

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The KNLR programme effectively improved leadership knowledge and skills and was positively evaluated by participants. Sixty-four Freeman frontal sinus stents were used to maintain patency in 46 patients. A cross-sectional survey of 60 somatizing patients who were part of a case-control study, selected by consecutive sampling of 2668 patients who presented at the Family Medicine Clinic of University College Hospital Ibadan, Nigeria between May-August 2009.

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Group 3 medulloblastomas are characterized by frequent amplifications of the oncogene MYC, a high incidence of metastasis, and poor prognosis despite aggressive therapy. In this high-risk population, the tracking must be rigorous and involve the participation of the patient herself, earlier and more frequent clinical assessment, and the use of imaging screening. Contractile ability was estimated as the maximum force elicited by 121 mM KCl or 0.6 mM acetylcholine. Barotrauma was neither related to high pressures and volumes nor associated with increased mortality.

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Potent P2Y12 Inhibitor Therapy for All?: But What About Ethnicity? Immune checkpoint molecule PD-1 is one of the critical molecule balancing immune response and immunological tolerance.

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Successful use of intravenous immunoglobulin as initial monotherapy in Landau-Kleffner syndrome. The effect of MT-I on skin pigmentation was measured using a Chroma meter (reflectometer) after subcutaneous administration of implants containing 4 mg MT-I to guinea pigs. Functional Preference for Object Sounds and Voices in the Brain of Early Blind and Sighted Individuals. Accumulating evidence suggests an association between coronary heart disease and risk for cognitive impairment or dementia, but no study has systematically reviewed this association. Indeed, we have found that an ent-kaurene diterpene, ent-11alpha-hydroxy-16-kauren-15-one (KD), induced apoptosis via caspase-8 activation in human promyelocytic leukemia HL-60 cells.

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Treatment with cidofovir requires the routine use of prophylactic measures. Caroli Syndrome is a rare inherited disorder characterized by intrahepatic ductal dilation and liver fibrosis that leads to portal hypertension. A new stereotactic guide using a navigational computer is developed for stereotactic procedures. Association of persistent hypoglossal artery, multiple intracranial aneurysms, and polycystic disease. Bacterial pneumonia can induce uncontrolled and massive neutrophil recruitment ultimately leading to acute respiratory distress syndrome and epithelium damage.

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Bone marrow mesenchymal stem cells have been considered to differentiate into cells in bone, cartilage, tendon, muscle, and fat. We performed whole human genome expression analysis in placenta tissue (normal and T21) samples in order to investigate gene expression into the pathogenesis of trisomy 21 (T21) placenta. Here we report on the water solubilization of quantum dots using lipid encapsulation. Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells.

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Ten children with early B-cell lineage acute lymphoblastic leukemia were evaluated by cosyntropin (corticotropin (1-24)) stimulation testing before initiation of dexamethasone therapy and every 4 weeks thereafter until adrenal function returned to normal. Identification by selective ion monitoring of 1-methyl-1,2,3,4-tetrahydro-beta-carboline in human platelets and plasma after ethanol intake. Substructure observed throughout the GS suggests further Quaternary fragmentation and a role for rivers. Our field experiment was a completely randomized block design with three replicates for five farming systems which included: Conventional clean till, conventional long rotation, conventional no-till, organic clean till, and organic reduced till. In this study the mechanisms underlying these events were explored.

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An easy MR-based measurement of the ratio of the size of the iliocapsularis to that of adjacent anatomical structures such as the rectus femoris muscle might be helpful in everyday clinical use. Histological changes of nerve tissue in the region of the hypothalamus after experimental intervention Several studies suggested that individuals lacking the C allele of the C1858T PTPN22 gene polymorphism may have reduced capacity to downregulate T-cell response.

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The amount of use made of post-aural aids issued through the National Health Service was investigated by monitoring the discharge rate of zinc air cells supplied to two matched groups of patients. Participants were 61 sexually abused and 57 nonsexually abused women. This study demonstrates that the registration error associated with this new mini-navigation system compares favourably with the known registration error associated with traditional navigation systems. Experience and dissection device are more relevant than patient-related factors for operation time in laparoscopic sigmoid resection-a retrospective 8-year observational study.

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Integrating mental health professionals in residencies to reduce health disparities. This powerful technology has been widely employed to manipulate gene expression in mammalian and human cells, elucidate signal pathways and identify gene functions in a whole-genome scale. Students responded anonymously at the end of their first year of medical school to surveys which included DREEM, JHLES, single-item global LE assessment variables, and demographics questions.

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Studies on the esterase of tubercle bacilli and various strains of acid-fast bacilli. These results suggest that breast density is related to tumor size, lymph node status, and lymphatic or vascular invasion in screen-detected cancers.

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Results from longitudinal analyses were similar to cross-sectional results, except for self-efficacy: no differences between early stages in self-efficacy were found, whereas self-efficacy predicted these early stage transitions. Socioeconomic status and organ damage in Mexican systemic lupus erythematosus women. This result demonstrates that the association between high ACTH/corticosteroid levels and a low behavioural reactivity is not genetically controlled. Pregnancy-associated plasma protein-A proteolytic activity in rat vertebral cell cultures: stimulation by dexamethasone--a potential mechanism for glucocorticoid regulation of osteoprogenitor proliferation and differentiation.

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We analyzed the distribution of mRNA for the main GABA-transporter subtype in the hippocampus, GAT-1, in adult rats. A pragmatic randomized control trial was undertaken to compare the minimum intervention dentistry (MID) approach, based on the atraumatic restorative treatment procedures (MID-ART: Test), against the standard care approach (Control) to treat early childhood caries in a primary care setting.

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Self-evaluations of minority group members revealed assimilation effects in response to in-group comparisons and contrast effects in response to out-group comparisons. The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin. Because the class size was two to three times larger than the normal tutorial group, suitable modifications were made (formation of floating groups around defined learning tasks, formal presentations, written reports, and evaluations by students and tutor). In human beings, sacrococcygeus ventralis is seen only during fetal life.

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Three cases, detected in utero and followed through the early neonatal period, were assessed with colour-flow Doppler imaging in an attempt to determine whether the clefts were associated with any demonstrable vascular disturbance. To find a new strategy for designing porphyrin-based organogelators, hydrogen-bond-donating (carboxylic acid)/accepting (pyridine) substituents or electron-donating (dialkylamino)/withdrawing (pyridine) substituents were introduced into peripheral positions of a porphyrin (1cp or 1ep, respectively), and the gelation properties were compared with those of symmetrical reference compounds bearing two pyridyl substituents or two ester groups (1pp or 1ee, respectively). Usefulness of the Dubowitz scale, particularly its neurological parameters, for evaluation of the maturity of sick newborn infants In an apparent feedback loop, monocytes were found to regulate scar resolution. Reduction of myocardial infarct size by a fluorocarbon-oxygenated reperfusate.

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Using sediment microbial fuel cells (SMFCs) for bioremediation of polycyclic aromatic hydrocarbons (PAHs). The inhibition of organiz nitro reductase by aureomycin in cell-free extracts. Four of five cell lines with homozygous p53 mutations at codon 273 (273His), contained p53 which had the ability to bind to p53 DNA binding sequences and transactivate. These data indicate that myeloma cells can affect host immunity by priming DC towards a maturation state favoring the generation of T cells with a regulatory rather than an effector phenotype. Oncologic defects resulting from extremity amputations are often extensive and require substantial soft tissue for reconstruction.

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Epidemiological aspects of typhoid fever in the province of Pisa. Management of neovascular age-related macular degeneration: current state-of-the-art care for optimizing visual outcomes and therapies in development. Peptide segment coupling in aqueous medium: silver ion activation of the thiolcarboxyl group. rRNA, extremely abundant in neurons, was considered to provide the greatest number of iron binding sites among cytoplasmic RNA species. As a result of the study, Abutilon indicum (L.) Sweet., Andrographis echioides (L.f.) Nees., Bacopa monnieri (L.) Wettst., Canarium strictum Roxb., Centella asiatica (L.) Urban., Senna auriculata (L.) Roxb.

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